3 March 2010
A paper published online by Nature describes how the Chin lab has used directed evolution to design a ribosome that reads four-letter codons instead of the normal three.
This development represents a big step for the field of synthetic biology, and opens up the possibility for designing orthogonal systems using new genetic codes and unnatural amino acids.
Watch Jason Chin deliver the Royal Society's Francis Crick Prize Lecture (26 November 2009)
